Analysis of iodine and selenium trace elements in umbilical cord blood in cretinous regions in northwest China in 1999
Analysis of iodine and selenium trace elements in umbilical cord blood in cretinous regions in northwest China in 1999
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DOI：
10.1007/bf02898062
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发表时间：
2002-04
影响因子：
4.7
通讯作者：
M. Su;D. Tian;Wen-sheng Li;Hu Zhao;Li-ping Li-Li-ping-Li-2154789562;Wu-hong Tan;Hongbing Song
中科院分区：
文献类型：
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作者：
M. Su;D. Tian;Wen-sheng Li;Hu Zhao;Li-ping Li-Li-ping-Li-2154789562;Wu-hong Tan;Hongbing Song
陕西省地处我国内陆中西部，是典型的碘缺乏病病区。目的了解陕西省亚临床克汀病病区补碘近20年后新生儿碘、硒水平的变化。我们从陕西省北部的宜君县（缺硒区）、南部的紫阳县（富硒区）和西安市临潼区（非克汀病对照区）的克汀病病区采集了56份脐带血。其中资阳市17个，临潼市20个，宜君市19个。同时测定脐血中碘、硒、锌、铜、铁、钙、镁7种微量元素，并对结果进行统计学处理。三个县的碘水平无显著差异。而资阳市硒含量最高，宜君市最低。除宜君县Ca含量较低外，其它微量元素Cu、Zn、Fe、Mg含量在三县间差异不显着。用多元回归的倒推法建立的回归方程为：Se= 0.180+ 0.00006654 Fe 0.006 Cu 0.005956 Mg+ 0.1
Shaanxi Province located at Midwest inland of China was a typical iodine deficient disorders region. To investigate iodine and selenium levels of neonates in the Shaanxi sub-clinical cretinism region of China after supplement of iodine salt for nearly twenty years. We collected 56 umbilical cord blood samples from cretinous regions of Yijun County (a selenium deficient region) north of Shaanxi Province and Ziyang County (a selenium-enriched region) south of the province and from Lintong in Xi’an (a non-cretinous region for control). Among these samples 17 were collected from Ziyang, 20 from Lintong and 19 from Yijun. Seven trace elements of iodine, selenium, zinc, copper, iron, calcium and magnesium in the umbilical cord blood samples were measured and the results were processed statistically. There were no significant differences in the levels of iodine among all three counties. However, the level of selenium in Ziyang was the highest and in Yijun it was the lowest. The other trace elements such as Cu Zn Fe and Mg showed no significant difference among the three counties except for the Ca level which was lower in Yijun. The regression equation was established with the backward method of multiple regression was: Se= 0.180+ 0.00006654 Fe 0.006 Cu 0.005956 Mg+ 0.1