Ocular Syphilis - Eight Jurisdictions, United States, 2014-2015
Ocular Syphilis - Eight Jurisdictions, United States, 2014-2015
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DOI：
10.15585/mmwr.mm6543a2
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发表时间：
2016-11-04
影响因子：
33.9
通讯作者：
Markowitz, Lauri
中科院分区：
文献类型：
--
作者：
Oliver, Sara E.;Aubin, Mark;Markowitz, Lauri
关于这个话题我们已经知道了什么？眼梅毒是梅毒感染的一种罕见表现，可引起各种眼部症状，包括视力丧失。2014年底至2015年报告了眼部梅毒集群。在美国，梅毒发病率自2000年以来有所上升，但对眼部梅毒病例知之甚少。这份报告补充了什么？八个司法管辖区审查了2014年，2015年或两者的梅毒监测和病例调查数据，发现在0.6%的梅毒病例中，患者的症状与眼部梅毒一致。大多数疑似病例为男性，半数为艾滋病毒抗体阳性者。HIV阳性和HIV阴性患者都出现了严重的后果，包括失明。这对公共卫生实践有什么影响？所有被诊断为梅毒的患者，如果出现眼部症状，应立即进行神经梅毒治疗，并进行正式的眼科检查。对患者和医务人员的教育对于识别梅毒的眼部表现和管理疾病后遗症至关重要。
What is already known about this topic?Ocular syphilis, an infrequent manifestation of syphilis infection, can cause a variety of eye symptoms, including vision loss. Clusters of ocular syphilis were reported from late 2014 to 2015. In the United States, syphilis rates have increased since 2000, but little is known about ocular syphilis cases.What is added by this report?Eight jurisdictions that reviewed syphilis surveillance and case investigation data from 2014, 2015, or both found that in 0.6% of syphilis cases, the patient had symptoms consistent with ocular syphilis. Most suspected cases were in males, and half were in HIV-positive persons. Severe outcomes, including blindness, occurred in both HIV-positive and HIV-negative patients.What are the implications for public health practice?All patients diagnosed with syphilis that exhibit ocular manifestations should immediately be treated for neurosyphilis and be referred for formal ophthalmologic examination. Education of both patients and providers is critical to identify ocular manifestations of syphilis and manage disease sequelae.