Corneal collagen-its role in maintaining corneal shape and transparency.

Corneal collagen-its role in maintaining corneal shape and transparency.
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DOI:
10.1007/s12551-009-0011-x
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发表时间:
2009-07-01
影响因子:
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通讯作者:
Meek, Keith M
Meek, Keith M
中科院分区:
其他
文献类型:
--
作者:
Meek, Keith M

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角膜胶原蛋白具有许多特性,使其能够发挥其作为组织内主要结构成分的作用。原纤维狭窄、直径均匀且组织精确。这些特性对于保持透明度以及提供维持形状和提供强度所需的生物力学先决条件至关重要。这篇综述从纳米到宏观层面描述了角膜胶原蛋白的结构和排列,以及这与维持角膜的形状和透明度的关系。
Corneal collagen has a number of properties that allow it to fulfil its role as the main structural component within the tissue. Fibrils are narrow, uniform in diameter and precisely organised. These properties are vital to maintain transparency and to provide the biomechanical prerequisites necessary to sustain shape and provide strength. This review describes the structure and arrangement of corneal collagen from the nanoscopic to the macroscopic level, and how this relates to the maintenance of the form and transparency of the cornea.