Projection Patterns of Corticofugal Neurons Associated with Vibrissa Movement.
Projection Patterns of Corticofugal Neurons Associated with Vibrissa Movement.
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DOI：
10.1523/eneuro.0190-18.2018
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发表时间：
2018-09
期刊：
影响因子：
3.4
通讯作者：
Furuta T
中科院分区：
文献类型：
--
作者：
Shibata KI;Tanaka T;Hioki H;Furuta T
啮齿动物积极地搅动它们的触须，当它们与周围的物体接触时，这使得啮齿动物能够收集有关环境的空间信息。大脑皮质的拂动运动指令对于触须运动的控制是至关重要的。使用清醒和头部固定的大鼠，我们研究了轴突投射模式和发射特性之间的相关性，在确定的第5层神经元的运动皮层，这是与触须运动。我们发现，皮层神经元发送轴突脑干发射优先在大幅度触须运动和corticocallosal神经元表现出高放电率在小触须运动或在安静的状态。这两种离皮层回路的差异可能与运动相关信息加工机制有关。
Rodents actively whisk their vibrissae, which, when they come in contact with surrounding objects, enables rodents to gather spatial information about the environment. Cortical motor command of whisking is crucial for the control of vibrissa movement. Using awake and head-fixed rats, we investigated the correlations between axonal projection patterns and firing properties in identified layer 5 neurons in the motor cortex, which are associated with vibrissa movement. We found that cortical neurons that sent axons to the brainstem fired preferentially during large-amplitude vibrissa movements and that corticocallosal neurons exhibited a high firing rate during small vibrissa movements or during a quiet state. The differences between these two corticofugal circuits may be related to the mechanisms of motor-associated information processing.