Free radical scavenging activity of extracts prepared from fresh leaves of selected Chinese medicinal plants

Free radical scavenging activity of extracts prepared from fresh leaves of selected Chinese medicinal plants
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DOI:
10.1016/j.fitote.2003.07.003
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发表时间:
2004-01-01
期刊:
影响因子:
3.4
通讯作者:
Ming, L
Ming, L
中科院分区:
医学3区
文献类型:
--
作者:
Hu, FL;Lu, RL;Ming, L

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以DPPH自由基为自由基,测定了300种木本药用植物鲜叶80%甲醇提取物的清除自由基活性。在筛选的植物中,有56种植物具有较强的自由基清除能力,IC 50值低于0.5 mg叶/ml。对这些植物的医疗用途的分析表明,它们中的大多数是用于止血,作为止血剂,抗菌剂或治疗痢疾。这些用途可能与单宁和类黄酮的含量直接相关,因此与其清除自由基的活性直接相关。(C)2003 Elsevier B. V.保留所有权利。
The free radical scavenging activity of the 80% methanolic extracts from fresh leaves of 300 Chinese medical woody plants was assessed with the aid of the stable DPPH radical. Among the plants screened, 56 species had strong free radical scavenging capacities, with IC50 values lower than 0.5 mg leaves per milliliter. Analysis of the medical uses of these plants showed that most of them are employed for their effects on hemostasis, as antiinflammatory, antimicrobial or for treatment of dysentery. These uses may be directly linked to the content in tannins and flavonoids and consequently to their free radical scavenging activities. (C) 2003 Elsevier B.V. All rights reserved.