A case report of angioedema during long-term (66 months) angiotensin converting enzyme inhibition therapy with enalapril.
A case report of angioedema during long-term (66 months) angiotensin converting enzyme inhibition therapy with enalapril.
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依那普利长期（66 个月）血管紧张素转换酶抑制治疗期间发生血管性水肿的病例报告。
DOI：
10.1253/jcj.60.166
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
M. Ishii
中科院分区：
文献类型：
--
作者：
H. Shionoiri;I. Takasaki;N. Hirawa;M. Kihara;E. Gotoh;T. Sasaki;H. Nakajima;M. Ishii
我们描述了一例在长期治疗中发生血管紧张素转换酶抑制剂引起的血管性水肿的罕见病例，患者为51岁的男性原发性高血压患者；这是日本报道的第三例此类不良反应。患者接受依那普利治疗66个月，主诉干咳，轻微且可耐受。最近，他注意到在服用晨间剂量的依那普利后，他的嘴巴、面部、嘴唇和舌头肿胀3至4小时。这些症状自发地减轻了，所以他继续服药。他再次指出，在第一次经历29天后，出现了类似的血管性水肿。在依那普利停药后，他没有再出现血管性水肿或干咳。此病例是在长期服用依那普利19930毫克的马来酸依那普利治疗过程中发生的。我们强调，在使用依那普利的过程中，随时可能发生血管性水肿。
We describe a rare case of ACE inhibitor-induced angioedema during long-term therapy in a 51-year-old male patient with essential hypertension; and this is the third case reported of this adverse reaction in Japan. The patient received enalapril for 66 months, and complained of a dry cough which was mild and tolerable. Recently, he noted tenderness of his mouth, face, swelling of lips and tongue for 3 to 4 h after taking his morning dose of enalapril. These symptoms abated spontaneously, so he continued taking the drugs. He again noted similar episodes of angioedema 29 days after the first experience. He had no further episodes of angioedema or dry cough after cessation of enalapril. This case of angioedema developed during long-term therapy with enalapril administered as 19,930 mg of enalapril maleate. We emphasize that angioedema may occur at any time during the use of enalapril.
有特发性血管性水肿病史的患者与 ACE 抑制剂相关的严重血管性水肿。
DOI：
--
发表时间：
1990
期刊：
JAMA : the journal of the American Medical Association
影响因子：
--
作者：
Orfan,N;Patterson,R;Dykewicz,MS
通讯作者：
Dykewicz,MS
家族性羧肽酶 N 缺乏症。
影响因子：
39.2
作者：
Mathews,KP;Pan,PM;Gardner,NJ;Hugli,TE
通讯作者：
Hugli,TE