PKCALC: a BASIC interactive computer program for statistical and pharmacokinetic analysis of data.

PKCALC: a BASIC interactive computer program for statistical and pharmacokinetic analysis of data.
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PKCALC:用于数据统计和药代动力学分析的 BASIC 交互式计算机程序。

DOI:
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发表时间:
1986
期刊:
Drug metabolism reviews (Softcover ed.)
影响因子:
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通讯作者:
R. Shumaker
R. Shumaker
中科院分区:
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文献类型:
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作者:
R. Shumaker

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PKCALC是一种用BASIC语言编写的交互式计算机程序,有助于:多受试者数据集的初始统计分析、实验数据的药代动力学分析、市售电子表格(例如,LOTUS 123)和药代动力学程序ESTRIP和PCNONLIN,以及数据图表的快速制备。浓度与时间数据可以手动输入程序,从数据交换格式(DIF)文件,或从PKCALC先前生成的数据文件。该程序有一个主菜单,列出了九个选项。这些包括但不限于,建立一个数据文件,该文件随后可由PCNONLIN读取,链接到扩充的ESTRIP副本以读取PKCALC数据文件,手动剥离曲线,以及利用CRT和行式打印机在线性或半对数轴上绘制多指数方程和/或主题数据。PKCALC在IBM PC、IBM XT、IBM AT和COMPAQ个人计算机上运行。
PKCALC, an interactive computer program written in BASIC, facilitates: initial statistical analysis of multisubject data sets, pharmacokinetic analysis of experimental data, transfer of data between commercially available electronic spread-sheets (e.g., LOTUS 123) and the pharmacokinetic programs ESTRIP and PCNONLIN, and rapid preparation of graphs of data. Concentration versus time data can be entered into the program manually, from a data interchange format (DIF) file, or from a data file previously generated by PKCALC. The program has a main menu listing nine options. These include, but are not limited to, setting up a data file which can subsequently be read by PCNONLIN, chaining to a copy of ESTRIP augmented to read PKCALC data files, stripping curves manually, and utilizing the CRT and a line printer to graph polyexponential equations and/or subject data on linear or semilogarithmic axes. PKCALC runs on the IBM PC, IBM XT, IBM AT, and COMPAQ personal computers.