National incidence rates for Acute Respiratory Distress Syndrome (ARDS) and ARDS cause-specific factors in the United States (2006-2014)
National incidence rates for Acute Respiratory Distress Syndrome (ARDS) and ARDS cause-specific factors in the United States (2006-2014)
复制标题
DOI：
10.1016/j.jcrc.2018.07.002
复制
发表时间：
2018-10-01
影响因子：
3.7
通讯作者：
McClain, Lydia I. Gilbert
中科院分区：
文献类型：
--
作者：
Eworuke, Efe;Major, Jacqueline M.;McClain, Lydia I. Gilbert
目的：评估急性呼吸窘迫综合征(ARDS)的发病率和ARDS相关死亡率。方法：在2006-2014年全国住院患者样本中确定ARDS的危险因素。结果：在6900万例急性呼吸窘迫综合征患者中，有1151.969例急性呼吸窘迫综合征患者和969,567例有危险因素的急性呼吸窘迫综合征患者。脓毒症(46.8%)、肺炎(44.9%)和休克(44.4%)是ARDS最常见的危险因素。报告最少的是胰腺炎(3.4%)、肺挫伤(1.4%)和溺水(0.2%)。发病率从180.7(2006年)增至220.8(2011年)，再从182.8(2012年)增至193.4(2014年)。肺炎、休克和败血症相关ARDS的发生率稳步上升，而输血和创伤相关ARDS的发生率下降。胃抽吸和胰腺炎相关的ARDS的趋势保持不变。与其他因素相比，休克、败血症和输血相关ARDS的死亡率更高。除输血和创伤相关的ARDS外，其他因素的死亡率下降。结论：虽然ARDS的发病率有所上升，但大多数危险因素的死亡率都下降了。在研究后期，输血和创伤相关ARDS的死亡率增加，需要进行研究以检查与这些危险因素相关的住院死亡增加的原因。由爱思唯尔公司出版。
Purpose: To estimate the incidence of Acute Respiratory Distress Syndrome (ARDS) and ARDS-related mortality rates.Methods: We identified patients with a risk factor for ARDS in the National Inpatient Sample (NIS) (2006-2014). Using survey-weighted descriptive statistics we estimated annual and overall proportions of ARDS cases.Results: From over 69 million discharges, 1,151.969 ARDS discharges and 969,567 ARDS discharges with a risk factor were identified. Sepsis (46.8%), pneumonia (44.9%) and shock (44.4%) were the most common ARDS risk factor. Pancreatitis (3.4%), pulmonary contusion (1.4%) and drowning (0.2%) were the least frequently reported. Incidence rates increased from 180.7 (2006) to 220.8 (2011) and again from 182.8 (2012) to 193.4 (2014). Incidence for pneumonia, shock and sepsis-associated ARDS increased steadily, while transfusion and trauma-associated ARDS declined. Trends for gastric aspiration and pancreatitis-related ARDS remained unchanged. Shock, sepsis and transfusion-associated ARDS had higher mortality rates compared to other factors. Except for transfusion and trauma-associated ARDS, mortality rates for other factors declined.Conclusion: Although increasing incidence for ARDS was observed, mortality rates declined for most risk factors. Mortality for transfusion and trauma-associated ARDS increased in the later study period, research is needed to examine reasons for the increasing in-hospital deaths associated with these risk factors. Published by Elsevier Inc.