Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample
Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study based on a community sample
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DOI：
10.1016/j.bbi.2020.06.021
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发表时间：
2020-10-01
影响因子：
15.1
通讯作者：
Gale, C. R.
中科院分区：
文献类型：
--
作者：
Batty, G. D.;Deary, I. J.;Gale, C. R.
背景：虽然某些传染病与社会经济劣势、心理健康问题和认知功能低下有关，但与新冠肺炎的关系要么不确定，要么未经检验。我们的目标是检查一系列心理社会因素与COVID-19患者住院的关系。方法：英国生物信息库是一项前瞻性的队列研究，包括大约50万名年龄在40-69岁之间的人，他们在2006至2010年间的研究诱导期间收集了有关心理社会因素和协变量的信息。结果：在431,051名英国研究成员的分析样本中，有908人因使用新冠肺炎而住院。在年龄和性别调整的分析中，新冠肺炎风险的增加与以下不利教育水平(优势比；95%可信区间：2.05；1.70，2.47)、收入(2.00；1.63，2，47)、地区贫困(2.20；1.86，2.59)、职业(1.39；1.14，1.69)、心理困扰(1.58；1.32，1.89)、精神健康(1.50；1.25，1.79)、神经质(1.19；1.00，1.42)，以及在两个认知功能测试中的表现--言语和数字推理(2.66；2.06，3.34)和反应速度(1.27；1.08，1.51)。对这些关联进行了分级(趋势的p值
Background: While certain infectious diseases have been linked to socioeconomic disadvantage, mental health problems, and lower cognitive function, relationships with COVID-19 are either uncertain or untested. Our objective was to examine the association of a range of psychosocial factors with hospitalisation for COVID-19.Methods: UK Biobank, a prospective cohort study, comprises around half a million people who were aged 40-69 years at study induction between 2006 and 2010 when information on psychosocial factors and covariates were captured. Hospitalisations for COVID-19 were ascertained between 16th March and 26th April 2020.Results: There were 908 hospitalisations for COVID-19 in an analytical sample of 431,051 England-based study members. In age- and sex-adjusted analyses, an elevated risk of COVID-19 was related to disadvantaged levels of education (odds ratio; 95% confidence interval: 2.05; 1.70, 2.47), income (2.00; 1.63, 2,47), area deprivation (2.20; 1.86, 2.59), occupation (1.39; 1.14, 1.69), psychological distress (1.58; 1.32, 1.89), mental health (1.50; 1.25, 1.79), neuroticism (1.19; 1.00, 1.42), and performance on two tests of cognitive function - verbal and numerical reasoning (2.66; 2.06, 3.34) and reaction speed (1.27; 1.08, 1.51). These associations were graded (p-value for trend