Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study
Stereotactic radiosurgery for patients with multiple brain metastases (JLGK0901): a multi-institutional prospective observational study
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DOI：
10.1016/s1470-2045(14)70061-0
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发表时间：
2014-04-01
期刊：
影响因子：
51.1
通讯作者：
Tsuchiya, Kazuhiro
中科院分区：
文献类型：
--
作者：
Yamamoto, Masaaki;Serizawa, Toru;Tsuchiya, Kazuhiro
背景：本研究旨在探讨无全脑放疗(WBRT)的立体定向放射外科治疗5~10个脑转移瘤患者的总存活率是否不低于2~4个脑转移瘤患者。方法：本前瞻性观察研究纳入1~10个新诊断的脑转移瘤患者，最大肿瘤体积10毫升，最长直径3厘米；总累积体积
Background We aimed to examine whether stereotactic radiosurgery without whole-brain radiotherapy (WBRT) as the initial treatment for patients with five to ten brain metastases is non-inferior to that for patients with two to four brain metastases in terms of overall survival.Methods This prospective observational study enrolled patients with one to ten newly diagnosed brain metastases Clargest tumour < 10 mL in volume and < 3 cm in longest diameter; total cumulative volume