Comparison of clinical picture between Yusho Yucheng cases and occupational PCB poisoning cases
Comparison of clinical picture between Yusho Yucheng cases and occupational PCB poisoning cases
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DOI：
10.1016/0045-6535(95)00315-0
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发表时间：
1996-02-01
期刊：
影响因子：
8.8
通讯作者：
Ikeda, M
中科院分区：
文献类型：
--
作者：
Ikeda, M
本文对浙江省余杭市和禹城市两起食物中毒事件的临床表现与职业性多氯联苯暴露进行了比较。结果发现，以血中PCB水平作为暴露强度的共同指标时，Yusho/Yucheng患者与职业性接触PCB工人的剂量-反应关系有很大不同;即使血中PCB水平相当，前者的临床表现也比后者严重得多。这一结论支持了多氯二苯并呋喃等化学物质在Yusho和Yucheng的病因学中发挥重要作用的建议。
Literature review on clinical picture was made on two food poisoning episodes of Yusho and Yucheng in comparison with occupational PCB exposures. It was found that the dose-response relationship is quite different between Yusho/Yucheng patients and workers occupationally exposed to PCBs, when PCB levels in blood were taken as a common indicator of exposure intensity; the clinical manifestations were much severer in the former than in the latter, even when blood PCB levels were comparable. This conclusion is in support of the suggestions that chemicals such as polychlorinated dibenzofurans should have played an important role in the etiology of Yusho and Yucheng.