Predicting the Need for Home Oxygen Therapy in Preterm Infants Born Before 28 Weeks' Gestation
Predicting the Need for Home Oxygen Therapy in Preterm Infants Born Before 28 Weeks' Gestation
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DOI：
10.1055/s-0035-1555122
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发表时间：
2016-01-01
影响因子：
2
通讯作者：
Clyman, Ronald I.
中科院分区：
文献类型：
--
作者：
Liebowitz, Melissa C.;Clyman, Ronald I.
目的 寻找一种可在出院前至少 3 至 4 周使用的预测因子，以识别需要家庭氧疗的婴儿。我们假设月经后 34 周 (PMA) 需要高水平呼吸支持的婴儿需要家庭供氧。研究设计 对 143 名妊娠不足 28 周的婴儿进行的单中心回顾性研究。我们确定了婴儿何时脱离各个级别的呼吸支持（机械通气、经鼻持续气道通气 [nCPAP] 或双相正压、鼻插管流量 >= 2L/min、鼻插管流量 < 2 L/min 或无呼吸支持）。我们的主要结局是需要家庭氧气。结果 在 34 周 PMA 时需要 nCPAP 的婴儿对家庭氧疗具有 100% 的阳性预测值。结论 在 34 周 PMA 时较高水平的呼吸支持可以预测家庭氧气的需求，有助于患者和家人做好出院准备。
Objective To discover a predictor, that could be used at least 3 to 4 weeks' before discharge, to identify infants who would need home oxygen therapy. We hypothesized that infants requiring a high level of respiratory support at 34 weeks' postmenstrual age (PMA) would require home oxygen.Study Design Single center retrospective study of 143 infants less than 28 weeks' gestation. We determined when infants weaned from each level of respiratory support (mechanical ventilation, nasal continuous airway pressure [nCPAP] or biphasic positive pressure, nasal cannula flow >= 2L/min, nasal cannula flow < 2 L/min or no respiratory support). Our primary outcome was need for home oxygen.Result Infants who required nCPAP at 34 weeks' PMA had a 100% positive predictive value for home oxygen therapy.Conclusion Higher levels of respiratory support at 34 weeks' PMA can predict the need for home oxygen and is useful in preparing patients and families for discharge.