Transient Part-Solid Nodules Detected at Screening Thin-Section CT for Lung Cancer: Comparison with Persistent Part-Solid Nodules

Transient Part-Solid Nodules Detected at Screening Thin-Section CT for Lung Cancer: Comparison with Persistent Part-Solid Nodules
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DOI:
10.1148/radiol.09090547
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发表时间:
2010-04-01
期刊:
影响因子:
19.7
通讯作者:
Lee, In Sun
Lee, In Sun
中科院分区:
医学1区
文献类型:
--
作者:
Lee, Sang Min;Park, Chang Min;Lee, In Sun

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目的:回顾性研究最初在肺癌薄层 CT 筛查中检测到的暂时性部分实性结节 (PSN) 的临床和计算机断层扫描 (CT) 特征,并确定可区分暂时性 PSN 和持续性 PSN 的预测因素。 材料和方法:本研究得到了机构审查委员会的批准。 2006年1月至2008年8月,从16777名接受胸部CT检查的人中,鉴定出93名具有126个PSN的人。回顾了 PSN 的临床特征和 CT 特征,并比较了短暂性和持续性 PSN 的临床和薄层 CT 特征。为了确定瞬时PSN的预测因素并评估预测性能,进行了逻辑回归分析和C统计分析。结果:126个PSN中88个(69.8%)是瞬时的。短暂性和持续性 PSN 之间存在显着差异 (P
Purpose:To retrospectively investigate clinical and computed tomographic (CT) features of transient part-solid nodules (PSNs) initially detected at screening thin-section CT for lung cancer and to determine predictive factors that may differentiate transient PSNs from persistent PSNs.Materials and Methods:This study was approved by the institutional review board. From January 2006 to August 2008, 93 individuals with 126 PSNs were identified from among 16 777 individuals who underwent chest CT. Clinical features and CT characteristics of PSNs were reviewed, and clinical and thin-section CT features were compared between transient and persistent PSNs. To identify predictive factors of transient PSNs and evaluate predictive performance, logistic regression analysis and C statistic analysis were performed.Results:Eighty-eight (69.8%) of 126 PSNs were transient. Between transient and persistent PSNs, there were significant differences (P