Implementation of strain rate as a bone remodeling stimulus.

Implementation of strain rate as a bone remodeling stimulus.
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将应变率作为骨重塑刺激的实施。

DOI:
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发表时间:
1995
期刊:
Journal of Biomechanical Engineering
影响因子:
--
通讯作者:
Y. Arramon
Y. Arramon
中科院分区:
--
文献类型:
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作者:
G. Luo;S. Cowin;A. Sadegh;Y. Arramon

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应变速率被实现为表面骨重塑的刺激。利用小梁骨结构的理想模型,比较了以应变速率作为刺激的表面重塑预测与以峰值应变大小作为刺激的预测。对于单轴加载的十字形,两种表面重塑刺激在周期性压缩载荷作用下预测的最终形状相同,但两种表面重塑刺激的最终形状演化路径不同。考虑了两种双轴载荷规则的小梁结构网格模型,一种是方形菱形单元网格,另一种是砖墙网格。对于这两种理想的小梁结构,比较表明,即使从这些明显不同的初始网格模式,两种表面重塑刺激在周期性压缩载荷下预测相同的最终形状,并且进化路径到最终形状是完全不同的。一般来说,这两种刺激不能预测相同的重塑,它们所预测的条件是不同的。建立的模型也适用于Goldstein et al.(1991)报告的动物实验数据,结果表明应变速率刺激预测骨重塑的结果与实验观察到的结果相似。
Strain rate is implemented as a stimulus for surface bone remodeling. Using idealized models for trabecular bone structures, the surface remodeling predictions using the strain rate as the stimulus are compared with the predictions using the peak strain magnitude as the stimulus. For a uniaxially loaded cruciform shape, the comparison shows that the two surface remodeling stimuli predict the same final shape under a periodic compressive load, but the two evolutionary paths to final shapes are different. Two biaxially loaded regular grid models of trabecular structure were considered, one a grid of square diamond shaped elements and the other a brick wall patterned grid. For both of these idealized trabecular structures, the comparison shows that the two surface remodeling stimuli predict the same final shape under a periodic compressive load, even from these distinctly different initial grid patterns, and the evolutionary paths to final shapes are quite different. In general the two stimuli do not predict the same remodeling and the conditions under which they do are derived. The models developed are also applied to the data from the animal experiments reported in Goldstein et al. (1991), and it is shown that the strain rate stimulus predicts bone remodeling similar to what was experimentally observed.
DOI: 10.1016/0021-9290(91)90384-y
发表时间: 1991-01-01
影响因子: 2.4
作者:
GOLDSTEIN, SA;MATTHEWS, LS;HOLLISTER, SJ
通讯作者: HOLLISTER, SJ
DOI: 10.1016/0021-9290(88)90008-5
发表时间: 1988-01-01
影响因子: 2.4
作者:
RICE, JC;COWIN, SC;BOWMAN, JA
通讯作者: BOWMAN, JA