Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia

Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia
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DOI:
10.1093/aje/kwi334
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发表时间:
2005-12-15
影响因子:
5
通讯作者:
Roberts, JM
Roberts, JM
中科院分区:
医学2区
文献类型:
--
作者:
Bodnar, LM;Ness, RB;Roberts, JM

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本研究的目的是量化炎症和甘油三酯在孕前体重指数(体重(kg)/身高(m)(2))和先兆子痫之间的关联中的中介作用。作者对55名先兆子痫妇女和165名孕妇进行了巢式病例对照研究,这些研究来自于“妊娠暴露和先兆子痫预防研究”(1997-2001年,宾夕法尼亚州匹兹堡)。采集的血清样本
The objective of this study was to quantify the mediating role of inflammation and triglycerides in the association between prepregnancy body mass index (weight (kg)/height (m)(2)) and preeclampsia. The authors conducted a nested case-control study of 55 preeclamptic women and 165 pregnant controls from the Pregnancy Exposures and Preeclampsia Prevention Study (Pittsburgh, Pennsylvania, 1997-2001). Serum samples collected at