Exploring spatial patterns of gene expression from Fruit Fly embryogenesis on the iPhone
Exploring spatial patterns of gene expression from Fruit Fly embryogenesis on the iPhone
复制标题
DOI：
10.1093/bioinformatics/bts518
复制
发表时间：
2012-11-01
期刊：
影响因子：
5.8
通讯作者：
Ye, Jieping
中科院分区：
文献类型：
--
作者：
Kumar, Sudhir;Boccia, Kelly;Ye, Jieping
移动技术通过用户友好的界面为无处不在的科学信息传播提供了独特的机会。因此，我们开发了一个新的FlyExpress移动应用程序，使越来越多的标准化原位杂交图像(>；100000)可用，其中包含果蝇(果蝇)胚胎发生过程中基因表达的空间模式。使用这一应用程序，科学家可以可视化和比较>；4000发育相关基因的表达模式。FlyExpress应用程序显示所选基因在不同视觉投影(例如侧向)下的表达模式，并根据它们的发育阶段显示它们。最终，我们设想在实验室中使用FlyExpress应用程序，科学家可能希望立即对已知的表达模式与在工作台上观察到的表达模式进行视觉比较，或者在广泛的科学讨论中显示感兴趣的表达模式。
Mobile technologies provide unique opportunities for ubiquitous distribution of scientific information through user-friendly interfaces. Therefore, we have developed a new FlyExpress mobile application that makes available a growing collection (>100 000) of standardized in situ hybridization images containing spatial patterns of gene expression from Drosophila melanogaster (fruit fly) embryogenesis. Using this application, scientists can visualize and compare expression patterns of >4000 developmentally relevant genes. The FlyExpress app displays the expression patterns of the selected gene for different visual projections (e. g. lateral) and displays them according to their developmental stages, which developmental time. Ultimately, we envision the use of FlyExpress app in the laboratory where scientists may wish to immediately conduct a visual comparison of a known expression pattern with the one observed on the bench top or to display expression patterns of interest during scientific discussions at large.