Tensile and compressive properties of the medial rabbit meniscus
Tensile and compressive properties of the medial rabbit meniscus
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DOI：
10.1243/095441105x34329
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发表时间：
2005-09-01
期刊：
影响因子：
1.8
通讯作者：
Athanasiou, KA
中科院分区：
文献类型：
--
作者：
Sweigart, MA;Athanasiou, KA
半月板材料特性的量化是至关重要的，为未来的组织工程研究创造了“金标准”参考。本研究的目的是确定兔半月板的压缩和周向拉伸性能。蠕变和恢复压痕实验上的弯月面使用蠕变压痕装置和分析通过有限元优化方法，以确定在六个地形位置的压缩材料性能。还检查了从兔半月板周向采集的样品的拉伸性能。结果表明，股骨侧的前部表现出最高的聚合模量（5 10 +/- 100 kPa）和剪切模量（240 +/- 40 kPa），而最低的聚合模量（120 +/- 30 kPa）和剪切模量（60 +/- 20 kPa）被发现在股骨侧的后部位置。拉伸样本的杨氏模量值为156.6 +/- 48.9 MPa，极限拉伸强度值为21.6 +/- 7.0 MPa，与其他动物模型中的值相似。这些材料特性的基线值将有助于未来的组织工程工作。
Quantification of the material properties of the meniscus is of paramount importance, creating a 'gold-standard' reference for future tissue engineering research. The purpose of this study was to determine the compressive and circumferential tensile properties in the rabbit meniscus. Creep and recovery indentation experiments were performed on the meniscus using a creep indentation apparatus and analysed via a finite element optimization method to determine the compressive material properties at six topographical locations. Tensile properties of samples taken circumferentially from the rabbit meniscus were also examined. Results show that the femoral side of the anterior portion exhibits the highest aggregate modulus (5 10 +/- 100 kPa) and shear modulus (240 +/- 40 kPa), while the lowest aggregate modulus (120 +/- 30 kPa) and shear modulus (60 +/- 20 kPa) were found on the femoral side of the posterior location. Values of 156.6 +/- 48.9 MPa for Young's modulus and of 21.6 +/- 7.0 MPa for the ultimate tensile strength of were found from the tensile samples, which are similar to the values found in other animal models. These baseline values of material properties will be of help in future tissue engineering efforts.