Gist memory in Alzheimer's disease: Evidence from categorized pictures
Gist memory in Alzheimer's disease: Evidence from categorized pictures
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DOI：
10.1037/0894-4105.20.1.113
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发表时间：
2006-01-01
期刊：
影响因子：
2.4
通讯作者：
Schacter, DL
中科院分区：
文献类型：
--
作者：
Budson, AE;Todman, RW;Schacter, DL
作者调查了要点记忆（由一组项目传达的一般意义，想法或要点），用于阿尔茨海默病（AD）患者的分类彩色照片，使用实验范式，其中参与者被指示在测试项目符合先前研究的类别时回答“是”，无论特定项目是否实际研究过。与对照组相比，患者赞同较少的研究项目和类似数量的非研究诱饵项目。在作者校正了基线误报率后，与对照组相比，患者对未研究的诱饵项目的认可水平较低，这表明他们的主旨记忆受损。这些研究结果的意义与AD患者的理解要点记忆和反应偏差进行了讨论。
The authors investigated gist memory (the general meaning, idea, or gist conveyed by a collection of items) for categorized color photographs in patients with Alzheimer's disease (AD) using an experimental paradigm in which participants are instructed to respond "yes" when a test item fits with a previously studied category, regardless of whether the specific item was actually studied. Compared with controls, the patients endorsed fewer studied items and similar numbers of nonstudied lure items. After the authors corrected for the baseline false-alarm rate, the patients showed a lower level of endorsements for nonstudied lure items compared with that of controls, suggesting that their gist memory is impaired. Implications of these findings for understanding gist memory and response bias in patients with AD are discussed.