Exanthematous diseases and the first epidemic of dengue to occur in Manaus, Amazonas State, Brazil, during 1998-1999
Exanthematous diseases and the first epidemic of dengue to occur in Manaus, Amazonas State, Brazil, during 1998-1999
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DOI：
10.1590/s0037-86822004000600009
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发表时间：
2004-12-01
影响因子：
2
通讯作者：
Guerra, Marcus Vinitius de Farias
中科院分区：
文献类型：
--
作者：
Figueiredo, Regina Maria Pinto De;Thatcher, Bedsy Dutary;Guerra, Marcus Vinitius de Farias
1998年，FMT/IMT-AM基金会实施了诊断急性未分化发热综合征的监测系统，目的是在巴西西部亚马逊雨林进行主动和被动监测，以查明和诊断急性发热的病原体。使用ELISA（酶联免疫吸附试验）CDC/OPAS或使用商业试剂盒检测IgM抗体的血清学试验进行诊断。共分析了8，557份来自临床疑似登革热病毒患者的血清样本。40%的血清标本对登革病毒呈ELISA阳性反应，26%的血清标本对风疹、麻疹、细小病毒、奥罗波什病毒和马亚罗病毒等其它散发性病毒性疾病呈ELISA阳性反应。
In 1998, the FMT/IMT-AM foundation implemented the surveillance system to diagnose acute undifferentiated febrile syndromes, with the objective of active and passive surveillance in Brazilian western Amazonian rainforest to identify and diagnose the etiologic agents of acute fever. The diagnoses were performed using serological tests to detect IgM antibodies by ELISA (Enzyme-linked-immunosorbent assay) CDC/OPAS or using commercial kits. A total of 8,557 serum samples obtained from patients with clinical suspicion of dengue virus were analyzed. ELISA positive reaction to dengue virus was presented by 40% of the serum samples and 26% of the serum samples had positive ELISA reactions to other exanthematous viral diseases, such as rubella, measles, parvovirus, Oropouche virus and Mayaro virus.