Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini

Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini
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A23187 和佛波酯对兔胰腺腺泡淀粉酶分泌的协同作用

DOI:
10.1016/0014-5793(84)81369-1
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发表时间:
1984
期刊:
影响因子:
3.5
通讯作者:
A. Fleuren
A. Fleuren
中科院分区:
生物学3区
文献类型:
--
作者:
J. De Pont;A. Fleuren

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The combination of the ionophore A23187 and the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA) stimulates amylase secretion from rabbit pancreatic acini up to a level equal to, or slightly higher than when carbachol is used as stimulant. Each of the two compounds alone gives only a minor stimulation. This synergistic effect of A23187 and TPA supports a role of protein kinase C in pancreatic enzyme secretion.
DOI: 10.1073/pnas.80.1.36
发表时间: 1983-01-01
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子: --
作者:
NIEDEL, JE;KUHN, LJ;VANDENBARK, GR
通讯作者: VANDENBARK, GR