Bending affects entropy of semiflexible polymers: Application to protein-DNA complexes.

Bending affects entropy of semiflexible polymers: Application to protein-DNA complexes.
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弯曲影响半柔性聚合物的熵:在蛋白质-DNA 复合物中的应用。

DOI:
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发表时间:
2009
期刊:
Physical review. E, Statistical, nonlinear, and soft matter physics
影响因子:
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通讯作者:
Y. Rabin
Y. Rabin
中科院分区:
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文献类型:
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作者:
S. Rappaport;Y. Rabin

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讨论了一类具有自发曲率的聚合物的广义蠕虫状链模型,并证明了这类天然弯曲聚合物的态密度和熵均高于直聚合物。这种效应通过增强dna弯曲蛋白的结合而改变了经典的Langmuir结合等温线。
We discuss a class of generalized wormlike chain models of polymers with spontaneous curvature and show that the density of states and consequently the entropy of such natively bent polymers are higher than that of straight ones. This effect changes the classical Langmuir binding isotherm by giving rise to enhanced binding of DNA-bending proteins.