Xanthogranulomatous pyelonephritis: a pathological, clinical and aetiological analysis of 87 cases.
Xanthogranulomatous pyelonephritis: a pathological, clinical and aetiological analysis of 87 cases.
复制标题
黄色肉芽肿性肾盂肾炎87例病理、临床及病因分析.
作者：
Parsons Ma;S. C. Harris;A. Longstaff;Grainger Rg
本文分析了1958 ~ 1983年87例黄色肉芽肿性肾盂肾炎（XPN），男14例，女73例，年龄13-85岁。临床、影像学及病理学检查均显示尿路梗阻（77.5%结石，17.5%肾盂输尿管连接部梗阻）及致病菌如大肠杆菌。在72%的病例中，从尿液中培养出大肠杆菌或变形杆菌。罕见的并发症包括鼻窦或肠道瘘管。我们认为，尿路梗阻和低毒力微生物感染的结合引发了XPN，相关脂质来源于肾盂脂肪组织。鉴别诊断的问题进行了讨论，在有关使用免疫细胞化学和电子显微镜。
Analysis of 87 cases of xanthogranulomatous pyelonephritis ( XPN ) from 1958 to 1983 (14 males, 73 females, ages 13-85) revealed an incidence of 1.4 cases/100 000 population per annum which is apparently increasing. Clinical, radiological and pathological investigations demonstrated universal urinary obstruction (77.5 per cent calculi, 17.5 per cent pelviureteric junction obstruction) and pathogenic organisms such as E. coli or Proteus were cultured from the urine in 72 per cent of cases. Rare complications included sinuses or fistulae to bowel. We believe that the combination of urinary obstruction and infection by organisms of low virulence initiate XPN , and that associated lipid is derived from renal pelvic adipose tissue. Problems of differential diagnosis are discussed in relation to the use of immunocytochemistry and electron microscopy.