Origin of concept of ischaemic heart disease.
Origin of concept of ischaemic heart disease.
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缺血性心脏病概念的起源。
DOI：
10.1136/hrt.50.3.209
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发表时间：
1983
影响因子：
--
通讯作者：
W. Proudfit
中科院分区：
文献类型：
--
作者：
W. Proudfit
有时候，一些疾病，如大痘、发热、腹泻、贫血、瘙痒等，也会被其他国家的人以贬义的方式命名，这往往是不公正的。由于缺血性心脏病概念的起源，一个公正的称谓应该是“英国病”。1768年，威廉·希伯登在内科医师学会的一次会议上描述了心绞痛，他是一位杰出的伦敦内科医生。从症状的角度来看，这种经典的描述几乎没有什么可补充的。突然死亡被认为是一种并发症。希伯登的做法是不以医院为基础，所以他有有限的机会进行尸检的病人谁经历了条件，或者他很少被咨询期间的绝症。他关于心绞痛的论文发表于1772年。1一本受欢迎的学术杂志《评论》在1772年3月号上完整地介绍了希伯登的贡献。2一位感兴趣的读者认出了希伯登所描述的症状，并指出希伯登不知道这种综合征的原因。第二个月，他写了一封感谢信给赫伯登医生，他在信中说，他“从来没有为自己的原因而烦恼，但把它归因于循环障碍或风湿病”。这封信的署名是“未知”，不到三个星期后，5月初，希伯登接到通知，说作者突然去世了。他安排约翰·亨特，伟大的解剖学家，病理学家和外科医生，做检查。当时，爱德华詹纳作为亨特家的居民和大师的学生，两年的任期即将结束，他参加了尸检。同年11月，赫伯登向医学院报告说：“由于这不是由于任何畸形，或病态的破坏部分必要的生活，我们不必绝望找到治愈。“希伯登的“未知”corres的身份-
Geographic designations sometimes have been given to diseases such as the great pox, febrile conditions, diarrhoeas, anaemias, and itches, often in a pejorative sense by those in other nations, often unjustly. A just appellation would be "British disease" for ischaemic heart disease, because of the origin of the concept. William Heberden was a prominent London physician when he described angina pectoris at a meeting of the College of Physicians in 1768. This classic description left little to be added from the standpoint of symptoms. Sudden death was mentioned as a complication. Heberden's practice was not hospital-based, so he had limited opportunity for postmortem examination of patients who had experienced the condition, or perhaps he seldom was consulted during the terminal illness. His paper on angina pectoris was published in 1772.1 A popular magazine for the scholarly, Critical Review, published a complete account of Heberden's contribution in its March 1772 issue.2 An interested reader recognised his symptoms as those described and noted that Heberden did not know the cause of the syndrome. The next month he wrote an appreciative letter to Dr Heberden in which he stated he had "never troubled myself much about the cause of it, but attributed it to an obstruction of the circulation or a species of rheumatism".3 He followed this remarkable speculation by a request that Heberden arrange a postmortem examination on his body, "if it please God to take me away suddenly". The letter was signed "Unknown" and less than three weeks later, early in May, Heberden was notified that the writer had died suddenly. He arranged for John Hunter, the great anatomist, pathologist, and surgeon, to do the examination. At the time, Edward Jenner was nearing the end of a two year term as a resident in Hunter's home and student of the master, and he attended the postmortem examination.4 Hunter found nothing to account for angina pectoris. In November of the same year Heberden reported to the College of Physicians that, "Since it was not due owing to any malconformation, or morbid destruction of parts necessary to life, we need not despair of finding a cure." The identity of Heberden's "Unknown" corres-