ELECTRICAL-STIMULATION INDUCED SPHINCTER FATIGUE DURING VOIDING

ELECTRICAL-STIMULATION INDUCED SPHINCTER FATIGUE DURING VOIDING
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DOI:
10.1016/s0022-5347(17)36784-8
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发表时间:
1992-09-01
期刊:
影响因子:
6.6
通讯作者:
ELHILALI, MM
ELHILALI, MM
中科院分区:
医学1区
文献类型:
--
作者:
LI, JS;HASSOUNA, M;ELHILALI, MM

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刺激骶神经以诱导排尿通常与同时收缩横纹括约肌有关,从而使排尿困难或不可能。发现有必要切断部分骶神经,以促进刺激排尿。本实验的一个主要目的是评估使用电刺激来疲劳括约肌以达到同样结果的可行性。为了比较切断根状括约肌和疲劳横纹括约肌的效果,测量了膀胱出口阻力。刺激S2神经的电压为3V,频率为35赫兹,持续时间为100微秒,持续时间为5~10秒。刺激S2神经后,刺激阴部神经,直到出现括约肌疲劳。诱导括约肌疲劳的最佳参数为3V、100~500赫兹、100微秒。15-20秒。压力-流量联合研究表明,在通过刺激实现膀胱排空方面,通过阴部神经疲劳括约肌与切断括约肌一样好。
The stimulation of the sacral nerves to induce voiding is often associated with simultaneous contraction of the striated sphincter rendering micturition difficult or impossible. Rhizotomy of some sacral nerves was found to be necessary to facilitate voiding with stimulation. An main objective in the present experiment was to evaluate the feasibility of achieving the same result using electrical stimulation to fatigue the sphincter. In order to compare the effect of rhizotomy and fatiguing striated sphincter, the bladder outlet resistance was measured. S2 nerves were stimulated with 3 V, 35 Hz and 100-mu-sec duration for 5 to 10 sec. Following S2 nerves stimulation the pudendal nerve was stimulated till we obtained sphincteric fatigue. The optimal parameter to induce sphincter fatigue were 3 V, 100-500 Hz and 100-mu-sec. for 15-20 sec. The,combined pressure-flow studies showed that fatiguing the sphincter via the pudendal nerve using these parameters was as good as cutting it in achieving bladder emptying with stimulation.