A latent reaction in a model GFP chromophore revealed upon confinement: photohydroxylation of ortho-halo benzylidene-3-methylimidazolidiones via an electrocylization process.
A latent reaction in a model GFP chromophore revealed upon confinement: photohydroxylation of ortho-halo benzylidene-3-methylimidazolidiones via an electrocylization process.
复制标题
模型 GFP 发色团中的潜在反应在限制后显露出来：通过电环化过程进行邻卤亚苄基-3-甲基咪唑烷二酮的光羟基化。
作者：
Shampa R. Samanta;J. P. Da Silva;Anthony Baldridge;L. Tolbert;V. Ramamurthy
研究了卤素取代的GFP模型发色团在乙腈溶液中的激发态行为和在水中辛酸胶囊提供的受限环境中的激发态行为。在邻位、间位和对位卤素取代的GFP发色团中，只有邻位化合物产生了一种新的产物，该产物是由羟基对卤素进行了前所未有的光取代得到的。这种不同寻常的反应突显了受限空间在导致一些无法实现的光反应方面的重要性。
Excited state behavior of halogen substituted model GFP chromophores was investigated in an acetonitrile solution and in a confined environment provided by an octa acid capsule in water. Of the ortho, meta, and para halogen substituted GFP chromophores only the ortho compounds gave a new product resulting from an unprecedented photosubstitution of halogens by the hydroxyl group. This unusual reaction highlights the importance of confined spaces in bringing about some unattainable photoreactions.