Effect of particle size of an amorphous calcium phosphate filler on the mechanical strength and ion release of polymeric composites
Effect of particle size of an amorphous calcium phosphate filler on the mechanical strength and ion release of polymeric composites
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DOI：
10.1002/jbm.b.30561
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发表时间：
2007-01-01
影响因子：
3.4
通讯作者：
Skrtic, D.
中科院分区：
文献类型：
--
作者：
Lee, Soo-Young;Regnault, W. F.;Skrtic, D.
无定形磷酸钙（ACP）颗粒在树脂基体中的随机聚类被认为会降低其聚合复合材料的强度。本研究的目的是阐明球磨对ACP填料粒径分布（PSD）的影响，并评估磨后ACP在甲基丙烯酸酯树脂中的分散是否足以增强填料/基体的相互作用，从而提高双轴抗折强度（BFS），同时不影响复合材料的再矿化潜力。采用PSD分析、x射线衍射、热重和化学分析、红外光谱和扫描电镜对未磨和湿磨氧化锆杂化ACP （Zr-ACP）填料进行了表征。复合样品由光活化的三元甲基丙烯酸酯树脂与未研磨或研磨的Zr-ACP的质量分数为40%的混合物制成，评估BFS（干和湿）以及钙和磷酸盐离子释放到盐水溶液中的情况。虽然铣削对填料的结构、组成和形貌/拓扑没有明显影响，但可以显著降低Zr-ACP颗粒的平均尺寸（中位数直径d(m)=0.9 +/- 0.2 μ m）和PSD的扩散。研磨后的Zr-ACP在树脂中的分散性更好，即使在水浸泡后，复合材料的BFS也得到了改善，并且离子释放谱也令人满意。基于Zr-ACP填料的抗脱矿/再矿ACP复合材料的机械稳定性的改善可能有利于潜在地扩大其牙科用途。(c) 2006 .中国生物医学工程学报* [J] .中国生物医学工程学报，32 (4):444 - 444,2007
The random clustering of amorphous calcium phosphate (ACP) particles within resin matrices is thought to diminish the strength of their polymerized composites. The objective of this study was to elucidate the effect of ball-milling on the particle size distribution (PSD) of ACP fillers and assess if improved dispersion of milled ACP in methacrylate resin sufficiently enhanced filler/matrix interactions to result in improved biaxial flexure strength (BFS), without compromising the remineralizing potential of the composites. Unmilled and wet-milled zirconia-hybridized ACP (Zr-ACP) fillers were characterized by PSD analysis, X-ray diffraction, thermogravimetric and chemical analysis, infrared spectroscopy, and scanning electron microscopy. Composite specimens made from a photoactivated, ternary methacrylate resin admixed with a mass fraction of 40% of un-milled or milled Zr-ACP were evaluated for the BFS (dry and wet) and for the release of calcium and phosphate ions into saline solutions. While having no apparent effect on the structure, composition, and morphology/topology of the fillers, milling significantly reduced the average size of Zr-ACP particulates (median diameter, d(m)=0.9 +/- 0.2 mu m) and the spread of their PSD. Better dispersion of milled Zr-ACP in the resins resulted in the improved BFS of the composites, even after aqueous soaking, and also gave a satisfactory ion release profile. The demonstrated improvement in the mechanical stability of anti-demineralizing/remineralizing ACP composites based on milled Zr-ACP filler may be beneficial in potentially extending their dental utility. (c) 2006 Wiley Periodicals, Inc.* J Biomed Mater Res Part B: Appl Biomater 80B: 11-17, 2007