The endothelial-mesenchymal transition (EndMT) and tissue regeneration.
The endothelial-mesenchymal transition (EndMT) and tissue regeneration.
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内皮间质转化（EndMT）和组织再生。
DOI：
10.2174/1574888x09666140213154144
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发表时间：
2014-05
期刊：
影响因子：
--
通讯作者：
Wang, Jun
中科院分区：
文献类型：
--
作者：
Xiao, Lan;Gou, Yongchao;Lin, Yunfeng;Wang, Jun
近期研究使内皮-间充质转化（EndMT）作为上皮-间充质转化（EMT）的一个特殊视角受到关注。传统上，EndMT被认为是成纤维细胞和肌成纤维细胞的一个来源，并且它广泛地……
Recent studies have brought endothelial-mesenchymal transition (EndMT) as a special perspective of epithelial- mesenchymal transition (EMT) into eyes. Traditionally, EndMT is considered as a source for fibroblasts and myofibroblasts, and it is extensively investigated in physiologic cardiac development as well as in pathologic tumor and fibrosis. Recently, new studies have found that EndMT-transformed cells had 'stemness', which means they could differentiate into chondroblasts, osteoblasts, and adipoblasts in differential culture, respectively. This gives EndMT a bright application future in tissue engineering and regeneration, especially for the formation of cartilage and bone.