Common and distinct neural networks involved in fMRI studies investigating morality: an ALE meta-analysis
Common and distinct neural networks involved in fMRI studies investigating morality: an ALE meta-analysis
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DOI：
10.1080/17470919.2017.1357657
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发表时间：
2018-01-01
影响因子：
2
通讯作者：
Molenberghs, Pascal
中科院分区：
文献类型：
--
作者：
Eres, Robert;Louis, Winnifred R.;Molenberghs, Pascal
道德是理解是非所必需的重要社会结构。研究道德的神经成像研究使用了各种各样的范例，并涉及到许多不同的大脑区域。然而，目前尚不清楚道德任务之间的差异是否是导致这种不同发现的原因。因此，在本研究中，对123个数据集(包括1963名参与者)进行了一系列激活似然估计(ALE)荟萃分析来解决这个问题。ALE元分析揭示了一系列与所有道德任务相关的共同大脑区域，包括内侧前额叶皮质、外侧眼眶前额叶皮质、杏仁核、颞顶交界处和楔前叶。然而，个体和对比分析也揭示了与每种道德模式相关的独特网络，这表明不同的道德任务招募了专门的大脑区域。
Morality is an important social construct necessary for understanding what is right and wrong. Neuroimaging studies investigating morality have used a wide variety of paradigms and implicated many different brain areas. Yet, it remains unclear whether differences amongst morality tasks are the cause for such heterogeneous findings. Therefore, in the present study, a series of activation likelihood estimation (ALE) meta-analyses were conducted on 123 datasets (inclusive of 1963 participants) to address this question. The ALE meta-analyses revealed a series of common brain areas associated with all moral tasks, including medial prefrontal cortex, lateral orbitofrontal cortex, amygdala, temporoparietal junction, and precuneus. However, individual and contrast analyses also revealed unique networks associated with each moral modality, suggesting that different moral tasks recruit specialised brain regions.