DIAGNOSIS OF COLIFORM INFECTION IN ACUTELY DYSURIC WOMEN
DIAGNOSIS OF COLIFORM INFECTION IN ACUTELY DYSURIC WOMEN
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DOI：
10.1056/nejm198208193070802
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发表时间：
1982-01-01
影响因子：
158.5
通讯作者：
HOLMES, KK
中科院分区：
文献类型：
--
作者：
STAMM, WE;COUNTS, GW;HOLMES, KK
通过尿道、阴道、中段尿和膀胱尿培养，对诊断有症状妇女下尿路大肠菌群感染的传统标准进行了重新评估。传统的诊断标准，每毫升中段尿液中有105个细菌，仅识别出51%膀胱尿液含有大肠杆菌的女性。发现最佳诊断标准为≥。102个细菌/ml（灵敏度，0.95;特异性，0.85）。尽管在以前对无症状妇女的研究中，每毫升中段尿中分离出< 105个大肠菌群具有较低的预测价值，但≥ 105个大肠菌群的标准的预测价值是低的。在大肠菌群感染率超过50%的有症状的妇女中，每毫升102个高（0.88）。因此，临床医生和微生物学家可能应该改变他们的方法来诊断和治疗妇女急性症状大肠菌群感染的下尿路。
Conventional criteria for diagnosing coliform infection of the lower urinary tract in symptomatic women was reevaluated by obtaining cultures of the urethra, vagina, midstream urine and bladder urine. The traditional diagnostic criterion, .gtoreq. 105 bacteria per ml of midstream urine, identified only 51% of the women whose bladder urine contained coliforms. The best diagnostic criterion was found to be .gtoreq. 102 bacteria per ml (sensitivity, 0.95; specificity, 0.85). Although isolation of < 105 coliforms per ml of midstream urine has had a low predictive value in previous studies of asymptomatic women, the predictive value of the criterion of .gtoreq. 102 per ml was high (0.88) among symptomatic women in whom the prevalence of coliform infection exceeded 50%. Thus, clinicians and microbiologists probably should alter their approach to the diagnosis and treatment of women with acute symptomatic coliform infection of the lower urinary tract.