The response of the rabbit subsynovial connective tissue to a stress-relaxation test
The response of the rabbit subsynovial connective tissue to a stress-relaxation test
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DOI：
10.1002/jor.21547
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发表时间：
2012-03-01
影响因子：
2.8
通讯作者：
Amadio, Peter C.
中科院分区：
文献类型：
--
作者：
Morizaki, Yutaka;Vanhees, Matthias;Amadio, Peter C.
腕管中的滑膜下结缔组织（SSCT）可能在腕管综合征（CTS）的病因学中发挥作用，但SSCT的材料特性仍不清楚。因此，我们在兔模型中研究了SSCT的机械响应。使用24只兔尸体爪进行机械测试;使用两只爪进行扫描电子显微镜（SEM）成像。在测试正常的肌腱偏移，分为第三手指屈趾浅肌（FDS）肌腱被拉到位移2，3.5，5，或8？mm，保持在该位置直到力衰减，然后重复该过程。FDS的正常偏移平均为4.8？第二峰值力的第一峰值力在2？mm组为0.98（SD=0.16），显著高于其他组（3.5？mm：0.74、5 mm、0.63和8 mm：0.59; p2？mm表示生理肌腱偏移范围内的SSCT损伤。这些数据可能有助于理解与SSCT纤维化相关的CTS中的SSCT机制。(C)2011年由Wiley Periodicals，Inc.出版的骨科研究学会。J Orthop Res 30：443447，2012
The subsynovial connective tissue (SSCT) in the carpal tunnel may play a role in the etiology of carpal tunnel syndrome (CTS), yet the material properties of the SSCT remain unclear. Thus, we investigated the mechanical response of the SSCT in a rabbit model. Twenty-four rabbit cadaver paws were used for mechanical testing; two paws were used for scanning electron microscopy (SEM) imaging. After testing normal tendon excursion, the divided third digit flexor digitorum superficialis (FDS) tendon was pulled to displacements of 2, 3.5, 5, or 8?mm, maintained at that position until force decay, and then the process was repeated. Normal excursion of the FDS averaged 4.8?mm. The ratio of the second peak force to the first peak force in the 2?mm group was 0.98 (SD=0.16), which was significantly higher than the other groups (3.5?mm: 0.74, 5mm, 0.63, and 8 mm: 0.59; p2?mm suggests damage to the SSCT within the physiological tendon excursion. These data may be useful in understanding SSCT mechanics in CTS, which is associated with SSCT fibrosis. (C) 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:443447, 2012