The Yersinia high-pathogenicity island is present in different members of the family Enterobacteriaceae
The Yersinia high-pathogenicity island is present in different members of the family Enterobacteriaceae
复制标题
DOI：
10.1016/s0378-1097(00)00005-7
复制
发表时间：
2000-02-15
影响因子：
2.1
通讯作者：
Carniel, E
中科院分区：
文献类型：
--
作者：
Bach, S;de Almeida, A;Carniel, E
致病性耶尔森氏菌中存在一个称为高致病性岛（HPI）的致病性岛。这个35至45 kb的岛携带参与铁载体耶尔森氏菌素合成、调节和转运的基因。最近，HPI也在各种大肠杆菌菌株中检测到。在这项研究中，HPI的家庭肠杆菌科的分布进行了调查。在67个分离物中，有18属52种。九间（百分之十三点四）以离岛为港口。这些分离物为3株E.大肠杆菌、一种多样柠檬酸杆菌和五种不同种类的克雷伯氏菌（肺炎克雷伯氏菌、大肠杆菌、臭鼻克雷伯氏菌、植物克雷伯氏菌和产酸克雷伯氏菌）。就像耶尔森氏菌，所有9个分离株都合成了HPI编码的铁抑制蛋白HMWP 1和HMWP 2。在K。在产酸菌菌株中，HPI的右端部分缺失，而岛的整个核心区域存在于所分析的八种其他肠杆菌菌株中。在大多数这些菌株中，HPI接壤的asn rRNA基因座，在耶尔森氏菌属。本报告因此证明了家庭肠杆菌科的各种成员之间的传播的HPI。(C)2000年，欧洲微生物学会联合会。由Elsevier Science B.V.出版，版权所有。
A pathogenicity island termed high-pathogenicity island (HPI) is present in pathogenic Yersinia. This 35 to 45 kb island carries genes involved in synthesis, regulation and transport of the siderophore yersiniabactin. Recently, the HPI was also detected in various strains of Escherichia coli. In this study, the distribution of the HPI in the family Enterobacteriaceae was investigated. Among the 67 isolates pertaining to 18 genera and 52 species rested. nine (13.4%) harbored the island. These isolates were three E. coli, one Citrobacter diversus and five Klebsiella of various species (Klebsiella pneumoniae, Klebsiella rhinoscleromatis, Klebsiella ozaenae, Klebsiella planticola, and Klebsiella oxytoca). As in Yersinia sp., all nine isolates synthesized the HPI-encoded iron-repressible proteins HMWP1 and HMWP2. In the K. oxytoca strain, the right-end portion of the HPI was deleted, whereas the entire core region of the island was present in the eight other enterobacteria strains analyzed. In most of these isolates, the HPI was bordered by an asn rRNA locus, as in Yersinia sp. This report thus demonstrates the spread of the HPI among various members of the family Enterobacteriaceae. (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.