Biological reaction to carbon fiber implants: the formation and structure of a carbon-induced "neotendon".

Biological reaction to carbon fiber implants: the formation and structure of a carbon-induced "neotendon".
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DOI:
10.1097/00003086-197803000-00049
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发表时间:
1978-03
影响因子:
4.2
通讯作者:
I. W. Foster;Z. Ráliš;B. Mckibbin;D. Jenkins
I. W. Foster;Z. Ráliš;B. Mckibbin;D. Jenkins
中科院分区:
医学2区
文献类型:
--
作者:
I. W. Foster;Z. Ráliš;B. Mckibbin;D. Jenkins

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取43只幼兔的跟腱和趾长屈肌腱切除,代之以纤维状碳纤维。对照组跟腱用丝线或尼龙缝线修复或不作更换。在一组碳替代跟腱手术中,同时切除了胫后神经。当完全发挥功能时,碳诱导的“新腱”迅速从年轻的成纤维细胞组织生长出来,这些组织生长在邻近神经血管束中的神经膜和血管外膜的松散间充质组织中。用丝绸或尼龙替换切除的跟腱并没有成功地生产出新的替代品。碳纤维作为指长屈肌腱的替代植入物效果不佳。
In 43 young rabbits, the tendo Achilles and flexor digitorum longus tendon were excised and replaced by filamentous carbon fiber. Tendo-Achilles in controls was repaired by silk or nylon sutures or left without replacement. Concurrent excision of the posterior tibial nerve was performed in one group of the carbon-replacing tendo-Achilles operations. When fully functioning, carbon-induced "neotendon" rapidly developed from young fibroblastic tissue outgrowths of the loose mesenchymal tissue of the perineurium and adventitia of the blood vessels in the adjacent neurovascular bundle. Silk or nylon replacement of the excised Achilles tendon did not lead to successful production of a new substitute. Carbon fibers were unsatisfactory for replacement implants for the flexor digitorum longus tendons.