Intra-abdominal mucinous adenocarcinoma of urachal origin: report of a case

Intra-abdominal mucinous adenocarcinoma of urachal origin: report of a case
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DOI:
10.1007/s00595-013-0620-7
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发表时间:
2014-06-01
期刊:
影响因子:
2.5
通讯作者:
Baba, Hideo
Baba, Hideo
中科院分区:
医学4区
文献类型:
--
作者:
Hirashima, Kotaro;Uchino, Ryojin;Baba, Hideo

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腹腔内粘液性囊性肿瘤在术前很难诊断。我们报告一个经组织学诊断为原发性脐尿管腺癌的病例:一种罕见的膀胱肿瘤。这个病例报告对临床医生来说很有趣。患者是一名86岁男性,因急性腹痛就诊。计算机断层扫描(CT)显示一个巨大的囊性肿块钙化,靠近膀胱顶端。剖腹手术发现一个巨大的腹腔内囊性肿块,附着在前腹壁和膀胱的上级。我们进行了腹腔镜辅助切除和部分囊肿切除术。囊性肿块大小约为15 x 14 x 11 cm,含有粘液物质。组织学检查显示,它延伸到膀胱壁的肌肉,其上皮细胞由乳头状形态增加的非典型细胞组成。粘液物质为糖蛋白,伴有变性脂肪组织,标本中部分可见钙化。因此,我们综合诊断为脐尿管起源的粘液性囊腺癌。
Intra-abdominal mucinous cystic tumors can be difficult to diagnose preoperatively. We report a case of histologically diagnosed primary urachal adenocarcinoma: a rare type of bladder tumor. This case report is interesting for clinicians. The patient was an 86-year-old man who presented with acute abdominal pain. Computed tomography (CT) showed a large cystic mass with calcification, near the apex of the urinary bladder. Laparotomy revealed a large intra-abdominal cystic mass adherent to the anterior abdominal wall and superior to the urinary bladder. We performed laparoscopic-assisted resection and partial cystectomy. The cystic mass measured approximately 15 x 14 x 11 cm and contained mucinous material. Histological examination revealed that it extended to the muscle of the bladder wall and that its epithelium was composed of atypical cells with increased papillary morphology. The mucinous material was glycoprotein with degenerative fatty tissue, and calcification was recognized partly in the specimen. Thus, we comprehensively diagnosed a mucinous cystic adenocarcinoma of urachal origin.