Illigerones A and B, two new long-chain secobutanolides from Illigera henryi W. W. Sm.

Illigerones A and B, two new long-chain secobutanolides from Illigera henryi W. W. Sm.
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Illigerones A 和 B,两种来自 Illigera henryi W. W. Sm 的新长链仲丁醇内酯。

DOI:
10.1016/j.phytol.2017.01.005
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发表时间:
2017
影响因子:
1.7
通讯作者:
Ding Zhong-Tao
Ding Zhong-Tao
中科院分区:
生物学4区
文献类型:
--
作者:
Li Xue-Jiao;Dong Jian-Wei;Cai Le;Wang Jia-Peng;Yu Nen-Xiang;Ding Zhong-Tao

文献摘要

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从香子兰中分得两个新的长链开环丁醇内酯化合物,即香子兰酮A(1)和B(2),以及五个已知化合物,即黄曲碱(3)、隐多灵碱(4)、β-谷甾醇(5)、胡萝卜苷(6)和豆甾醇(7)。W. SM.化合物1和2的结构经HRESIMS、EIMS、1D/2D NMR和电子圆二色谱(ECD)确证。化合物1对5种肿瘤细胞具有中等的细胞毒活性。这是首次从Hernandiaceae植物中分离到断丁醇内酯。
Two new long-chain secobutanolides, illigerones A (1) and B (2), together with five known compounds, actinodaphnine (3), cryptodorine (4),β-sitosterol (5), daucosterol (6), and stigmasterol (7) were isolated fromIlligera henryiW. W. Sm. The structures of1and2were identified by HRESIMS, EIMS, 1D/2D NMR, and electronic circular dichroism (ECD) spectra. Compound1exhibited the moderate cytotoxic activities against five tumour cells. This is the first report of secobutanolides isolated from plants of Hernandiaceae.