Contrast-enhanced sonography of autoimmune pancreatitis - Comparison with pathologic findings
Contrast-enhanced sonography of autoimmune pancreatitis - Comparison with pathologic findings
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DOI：
10.7863/jum.2004.23.2.199
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发表时间：
2004-02-01
影响因子：
2.3
通讯作者：
Tanaka, K
中科院分区：
文献类型：
--
作者：
Numata, K;Ozawa, Y;Tanaka, K
Objective.我们评估了对比增强谐波灰阶超声图像上的自身免疫性胰腺炎病变的血管分布，并与病理结果进行比较。方法.对6例自身免疫性胰腺炎患者进行了检查。所有患者在注射造影剂后20 - 50秒内屏住呼吸，同时通过对比增强谐波灰阶超声检查病变的血管分布（早期），并在注射后约90秒监测病变增强，同时患者屏住呼吸数秒（延迟期）。然后，我们比较了对比增强谐波灰阶超声图像上的血管与病理结果（纤维化和炎症）在所有病变。6个病灶中的3个病灶在皮质类固醇治疗前后也通过对比增强谐波灰阶超声进行了血管分布评估。结果自身免疫性胰腺炎病变表现出轻度（n = 1），中度（n = 3），或显着（n = 2），几乎整个病变在早期和延迟相增强。对比增强谐波灰阶超声图像上病变血管的分级与炎症的病理分级相关，与自身免疫性胰腺炎相关的纤维化分级呈负相关。激素治疗后，所有3个病灶的对比增强谐波灰阶超声图像上的血管减少。结论.灰阶谐波超声造影可用于评估自身免疫性胰腺炎病变的血管分布和类固醇治疗的疗效。关键词。自身免疫性胰腺炎;超声造影;病理结果。
Objective. We evaluated the vascularity of autoimmune pancreatitis lesions on contrast-enhanced harmonic gray scale sonographic images in comparison with the pathologic findings. Methods. Six patients with autoimmune pancreatitis were examined. All patients held their breath from 20 to 50 seconds after the injection of a contrast agent while the vascularity of the lesion was examined by contrast-enhanced harmonic gray scale sonography (early phase), and lesion enhancement was monitored at about 90 seconds after the injection while the patients held their breath for a few seconds (delayed phase). We then compared the vascularity on the contrast-enhanced harmonic gray scale sonographic images with the pathologic findings (fibrosis and inflammation) in all lesions. The vascularity of 3 of the 6 lesions was also evaluated by contrast-enhanced harmonic gray scale sonography before and after treatment with corticosteroids. Results. The autoimmune pancreatitis lesions exhibited mild (n = 1), moderate (n = 3), or marked (n = 2) enhancement throughout almost the entire lesions in both the early and delayed phases. The grade of lesion vascularity on the contrast-enhanced harmonic gray scale sonographic images correlated with the pathologic grade of inflammation and inversely correlated with the grade of fibrosis associated with autoimmune pancreatitis. The vascularity of all 3 lesions had decreased on the contrast-enhanced harmonic gray scale sonographic images after steroid therapy. Conclusions. Contrast-enhanced harmonic gray scale sonography may be useful for evaluating the vascularity of autoimmune pancreatitis lesions and the therapeutic efficacy of steroid therapy. Key words. autoimmune pancreatitis; contrast-enhanced sonography; pathologic findings.