Neonatal respiratory morbidity in the early term delivery
Neonatal respiratory morbidity in the early term delivery
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DOI：
10.1016/j.ajog.2012.07.022
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发表时间：
2012-10-01
影响因子：
9.8
通讯作者：
Gyamfi-Bannerman, Cynthia
中科院分区：
文献类型：
--
作者：
Ghartey, Kobina;Coletta, Jaclyn;Gyamfi-Bannerman, Cynthia
目的：本研究的目的是评估“早期”（37-38周）分娩的新生儿与39周分娩的新生儿呼吸系统疾病的风险。研究设计：我们对妊娠37（0/7）至39（6/7）周的单胎分娩进行了回顾性队列研究。我们的主要结局是复合呼吸道疾病。结果：在2273例37-39周分娩中，51% （n = 1169）在足月早期分娩。37-38周分娩的婴儿发生呼吸窘迫综合征、吸氧、持续气道正压通气和复合呼吸系统发病率的风险增加2倍（风险比[RR]， 2.9； 95%可信区间[CI]， 1.0-7.9；吸氧使用RR， 2.0; 95% CI, 1.4-2.9；持续气道正压通气RR， 1.9; 95% CI, 1.1-3.2；复合呼吸系统发病率RR， 2.0; 95% CI, 1.4-2.8）。结论：早期婴儿复合呼吸系统疾病风险增加2倍，支持将无指征分娩限制在妊娠bb0 = 39周的紧迫性。
OBJECTIVE: The purpose of this study was to evaluate the risk of respiratory morbidity in neonates delivered at "early term" (37-38 weeks) compared with those delivered at 39 weeks.STUDY DESIGN: We conducted a retrospective cohort study of singleton deliveries from 37(0/7) to 39(6/7) weeks' gestation. Our primary outcome was composite respiratory morbidity.RESULTS: Of 2273 deliveries at 37-39 weeks, 51% (n = 1169) delivered in the early term period. Infants delivered at 37-38 weeks had a 2-fold increased risk of respiratory distress syndrome, oxygen use, continuous positive airway pressure use, and composite respiratory morbidity (risk ratio [RR], 2.9; 95% confidence interval [CI], 1.0-7.9; oxygen usage RR, 2.0; 95% CI, 1.4-2.9; continuous positive airway pressure RR, 1.9; 95% CI, 1.1-3.2; composite respiratory morbidity RR, 2.0; 95% CI, 1.4-2.8).CONCLUSION: The 2-fold increased risk of composite respiratory morbidity of infants in the early term period supports the urgency for limiting nonindicated deliveries to >= 39 weeks' gestation.