Fatal Granulomatosis of the Respiratory Tract (Lethal Midline Granuloma-Wegener's Granulomatosis)
Fatal Granulomatosis of the Respiratory Tract (Lethal Midline Granuloma-Wegener's Granulomatosis)
复制标题
呼吸道致命肉芽肿病（致命中线肉芽肿-韦格纳肉芽肿病）
DOI：
10.1001/archotol.1959.00730040721007
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发表时间：
1959
影响因子：
--
通讯作者：
W. Schull
中科院分区：
文献类型：
--
作者：
I. Blatt;H. Seltzer;P. Rubin;A. Furstenberg;J. Maxwell;W. Schull
呼吸道致死性肉芽肿病是一种具有显著自然史、可识别的临床表现和可识别的病理特征的疾病。所有年龄段的男性、女性和儿童都是易感人群，其中许多人以前没有过敏或血管疾病的症状。最早的关于这种疾病的文献出现在1897年，当时McBride 1 1报道了一个奇怪的溃疡性肉芽肿性病变，“一个鼻子和脸迅速破坏的病例。“福代斯、2伍兹、3法尔基、6查特利尔、7克劳斯、8斯图尔特、13和其他人也报告了类似的病例。在1936年和1939年，Wegener 26，27发表了三个病例，其特征是鼻、鼻副窦、喉和肺的坏死性肉芽肿病，与“特殊肉芽肿性肾炎”有关。韦格纳认为，鼻子是疾病的原发部位，并应用术语“肉芽肿性肉芽肿病”的疾病过程。1897 - 1957年文献综述
Fatal granulomatosis of the respiratory tract is a disease with a noteworthy natural history, recognizable clinical manifestations, and identifying pathologic characteristics. Men, women, and children of all ages are susceptible, many of whom have no previous stigmata of allergic or vascular disease. The earliest reference to this disease appeared in 1897, when McBride1 1 reported bizarre ulcerative granulomatous lesions in "a case of rapid destruction of the nose and face." Similar cases have been reported by Fordyce, 2 Woods, 3 Falchi, 6 Chatellier, 7 Kraus, 8 Stewart, 13 and others. In 1936 and 1939, Wegener 26,27 published three cases characterized by necrotizing granulomatosis of the nose, nasal accessory sinuses, larynx, and lungs associated with a "peculiar granulomatous nephritis." Wegener believed that the nose was the primary site of the disease and applied the term "rhinogenous granulomatosis" to the disease process. A review of the available literature from 1897 to 1957