The Chloride Regulon of Halobacillus Halophilus: A Novel Regulatory Network for Salt Perception and Signal Transduction in Bacteria
The Chloride Regulon of Halobacillus Halophilus: A Novel Regulatory Network for Salt Perception and Signal Transduction in Bacteria
复制标题
嗜盐杆菌的氯调节子：细菌中盐感知和信号转导的新型调节网络
DOI：
10.1007/1-4020-3633-7_20
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发表时间：
2005
影响因子：
2.8
通讯作者：
Stephan H. Saum
中科院分区：
文献类型：
--
作者：
V. Müller;Stephan H. Saum
The moderately halophilic bacteria are a specialized group of organisms that require NaCl for growth. They grow with nearly the same rate over a rather wide range of external salt concentrations (0.5-2.0 M) which is evidence for effective mechanisms to cope with changing external salinities. Generally, growth of marine bacteria and moderate halophiles can be considered as being Na+-dependent, and Na+ is used for various bioenergetic reactions. However, of importance is not the presence of the ion per se, but the cells must maintain a sodium ion gradient (Na+ i< Na+ o) across their cytoplasmic membranes. Export of Na+ can be achieved by primary and secondary transport systems, but the latter, like Na+/H+ antiporters, for bioenergetic reasons are better suited as effective Na+ export systems operating at high external salt concentrations.In contrast to the well established role of the cation Na+ in the physiology of prokaryotes, little is known about the specific requirement for anions for growth and for the operation of specific cellular functions. The use of chloride salts in physiological studies with halophilic microorganisms is generally taken for granted and little thought is then devoted to the possibility that chloride may have more specific functions in the cell beyond serving as the counterion for the high concentrations of cations used in the growth media. In this review we will summarize the current status on the role of chloride in prokaryotes with a focus on the recently described novel function as a signal compound in the moderately halophilic bacterium Halobacillus halophilus.
大肠杆菌细胞色素 bo3 的还原态和共配体态中 CuB 的协调。
DOI：
10.1021/bi982885l
发表时间：
1999
期刊：
Biochemistry.
影响因子：
--
作者：
Ralle,M;Verkhovskaya,ML;Morgan,JE;Verkhovsky,MI;Wikstrom,M;Blackburn,NJ
通讯作者：
Blackburn,NJ