Fluorescence navigation with indocyanine green for detecting sentinel nodes in extramammary Paget's disease and squamous cell carcinoma
Fluorescence navigation with indocyanine green for detecting sentinel nodes in extramammary Paget's disease and squamous cell carcinoma
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DOI：
10.1111/j.1346-8138.2009.00595.x
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发表时间：
2009-02-01
影响因子：
3.1
通讯作者：
Morita, Eishin
中科院分区：
文献类型：
--
作者：
Tsujino, Yoshio;Mizumoto, Kazuo;Morita, Eishin
放射性同位素导航方法，这通常被用于识别前哨淋巴结，是不太有用的定位前哨淋巴结靠近原发性病变的乳房外佩吉特病的情况下，因为重叠的放射性从原发部位。我们在两名皮肤癌患者中应用了吲哚菁绿色（ICG）荧光导航来覆盖这一缺陷。使用电荷耦合器件摄像机能够在不切开皮肤的情况下实时可视化动态淋巴流。腹股沟皮肤上的前哨淋巴结与手持式伽玛探头是根据ICG荧光检测到的点与鳞状细胞癌患者的脚。前哨淋巴结活检使用荧光导航与ICG被证明是简单和可靠的。
The radioisotope navigation method, which has usually been used for identification of sentinel nodes, is less useful in locating sentinel nodes close to primary lesions in cases of extramammary Paget's disease because of overlapping radioactivity from the primary site. We applied fluorescence navigation with indocyanine green (ICG) in two patients with skin cancer to cover this defect. The use of a charge-coupled device camera enabled real-time visualization of dynamic lymph flow without skin incision. The inguinal skin over the identified sentinel node with a handheld gamma probe was in accordance with the point detected by ICG fluorescence in a patient with squamous cell carcinoma of the foot. Sentinel node biopsy using fluorescence navigation with ICG proved to be easy and reliable.