Mechanistic studies by sum-frequency generation spectroscopy: hydrolysis of a supported phospholipid bilayer by phospholipase A2.
Mechanistic studies by sum-frequency generation spectroscopy: hydrolysis of a supported phospholipid bilayer by phospholipase A2.
复制标题
DOI:
10.1002/anie.200904950
复制
发表时间:
2010-03
影响因子:
--
通讯作者:
Yujin Tong;Na Li;Huijin Liu;Aimin Ge;M. Osawa;S. Ye
中科院分区:
文献类型:
--
作者:
Yujin Tong;Na Li;Huijin Liu;Aimin Ge;M. Osawa;S. Ye
(Figure Presented) Sum mothers do'ave'em: Sum-frequency generation spectroscopy was used to investigate the hydrolysis mechanism of a dipalmitoylphosphatidylcholine bilayer by phospholipase A 2 (PLA 2). This study describes the structural changes and the hydrolysis mechanism in each leaflet (red and black) of a supported lipid bilayer at a molecular level.