Self-Assembly into Multicompartment Micelles and Selective Solubilization by Hydrophilic-Lipophilic-Fluorophilic Block Copolymers
Self-Assembly into Multicompartment Micelles and Selective Solubilization by Hydrophilic-Lipophilic-Fluorophilic Block Copolymers
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DOI：
10.1021/ma200032j
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发表时间：
2011-04-12
期刊：
影响因子：
5.5
通讯作者：
Laschewsky, Andre
中科院分区：
文献类型：
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作者：
Marsat, Jean-Noel;Heydenreich, Matthias;Laschewsky, Andre
采用可逆加成断裂链转移(RAFT)法连续三步合成了两亲性线型三元嵌段共聚物(ABC)。以低聚(环氧乙烷)单甲醚丙烯酸酯、丙烯酸苄酯和1H，1H-全氟丁基丙烯酸酯为单体，三嵌段共聚物由亲水性(A)、亲油性(B)和亲氟性(C)三个嵌段组成。系统地改变三亲共聚物的嵌段序列以提供所有可能的变体：ABC、ACB和BAC。所有块的玻璃化转变温度都低于0℃，在水溶液中观察到自组装成球形胶束聚集体，其中疏水核心经历了局部相分离，形成各种超微结构，如低温透射电子显微镜(Cryo-TEM)所示。亲油性和亲氟性嵌段分别选择性增溶了大量碳氢化合物和低摩尔质量氟碳化合物。
Amphiphilic linear ternary block copolymers (ABC) were synthesized in three consecutive steps by the reversible addition fragmentation chain transfer (RAFT) method. Using oligo(ethylene oxide) monomethyl ether acrylate, benzyl acrylate, and 1H,1H-perfluorobutyl acrylate monomers, the triblock copolymers consist of a hydrophilic (A), a lipophilic (B), and a fluorophilic (C) block. The block sequence of the triphilic copolymers was varied systematically to provide all possible variations: ABC, ACB, and BAC. All blocks have glass transition temperatures below 0 degrees C. Self-assembly into spherical micellar aggregates was observed in aqueous solution, where hydrophobic cores undergo local phase separation into various ultrastructures as shown by cryogenic transmission electron microscopy (cryo-TEM). Selective solubilization of substantial quantities of hydrocarbon and fluorocarbon low molar mass compounds by the lipophilic and fluorophilic block, respectively, is demonstrated.