Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions.
Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions.
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背侧和腹侧：纹状体子区域在目标指导作用的采集和性能中的独特作用。
DOI：
10.1016/j.nlm.2013.11.003
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发表时间：
2014-02
影响因子：
2.7
通讯作者：
Balleine BW
中科院分区：
文献类型：
--
作者：
Hart G;Leung BK;Balleine BW
相当多的证据表明，不同的神经过程介导的收购和性能的目标导向的工具性行动。而皮质背内侧纹状体电路的收购目标导向的行动似乎是至关重要的，皮质腹侧纹状体电路似乎调解工具性能，特别是动机控制性能。在这里，我们审查的证据表明，这些不同的机制，学习和性能构成两个不同的“流”控制工具条件反射。从这个角度来看，这些“流”之间的相互作用的监管成为一个相当重要的问题。我们描述的证据表明，基底外侧杏仁核，这是严重互连的背侧和腹侧的纹状体的子区域，协调这种相互作用提供输入的最终共同路径的行动作为一个关键组成部分的边缘运动接口。
Considerable evidence suggests that distinct neural processes mediate the acquisition and performance of goal-directed instrumental actions. Whereas a cortical-dorsomedial striatal circuit appears critical for the acquisition of goal-directed actions, a cortical-ventral striatal circuit appears to mediate instrumental performance, particularly the motivational control of performance. Here we review evidence that these distinct mechanisms of learning and performance constitute two distinct ‘streams’ controlling instrumental conditioning. From this perspective, the regulation of the interaction between these ‘streams’ becomes a matter of considerable importance. We describe evidence that the basolateral amygdala, which is heavily interconnected with both the dorsal and ventral subregions of the striatum, coordinates this interaction providing input to the final common path to action as a critical component of the limbic-motor interface.