Adhesion effects of a guanidinium ion appended dendritic "molecular glue" on the ATP-driven sliding motion of actomyosin.
Adhesion effects of a guanidinium ion appended dendritic "molecular glue" on the ATP-driven sliding motion of actomyosin.
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DOI：
10.1002/anie.200906139
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发表时间：
2010-04
影响因子：
--
通讯作者：
Kou Okuro;K. Kinbara;Kuniaki Takeda;Y. Inoue;A. Ishijima;T. Aida
中科院分区：
文献类型：
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作者：
Kou Okuro;K. Kinbara;Kuniaki Takeda;Y. Inoue;A. Ishijima;T. Aida
粘性末端：肌动蛋白和肌球蛋白的异向性结合物--肌动溶素--由含有9个悬挂的胍离子的水溶性树枝状“分子胶”稳定(见图；ATP=三磷酸腺苷，ADP=二磷酸腺苷)。ATP驱动的肌动蛋白细丝在肌动蛋白非功能化覆盖片上的滑动运动在高代树枝状大分子中减速或完全停止，但在低代树枝状大分子中不会。(附图)？2010 Wiley-VCH Verlag GmbH&Co.KGaA。
A sticky end: A heterotropic conjugate of actin and myosin-actomysin-is stabilized by a water-soluble dendritic "molecular glue" bearing nine pendant guanidinium ions (see picture; ATP = adenosine triphosphate, ADP = adenosine diphosphate). The ATP-driven sliding motion of actin filaments on a myosinfunctionalized coverslip is decelerated or totally arrested with a higher-generation dendrimer, but not with a lower-generation one. (Figure Presented) © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.