Facile and Highly RegiospecificSynthesis of 2-Aryl-Substituted Pyrazolidin-3-ones from α,β-Unsaturated N-Acylbenzotriazoles and Arylhydrazines
Facile and Highly RegiospecificSynthesis of 2-Aryl-Substituted Pyrazolidin-3-ones from α,β-Unsaturated N-Acylbenzotriazoles and Arylhydrazines
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DOI：
10.1055/s-0028-1083159
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发表时间：
2008-09
期刊：
影响因子：
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通讯作者：
Xiao-xia Wang;Wencun Wang;Y. Wen;Liang‐Nian He;Xiangming Zhu
中科院分区：
文献类型：
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作者：
Xiao-xia Wang;Wencun Wang;Y. Wen;Liang‐Nian He;Xiangming Zhu
以三乙胺为助催化剂，在THF中实现了芳肼与α，β-不饱和N-酰基苯并三唑的双加成反应。该反应具有高度的区域选择性，并以中等至良好的产率得到各种2-芳基取代的吡唑烷-3-酮。
The bis-addition of arylhydrazines to α,β-unsaturated N-acylbenzotriazoles to form heterocyclic compounds was achieved in refluxing THF by using triethylamine as promoter. The reaction was highly regioselective and various 2-aryl-substituted pyrazolidin-3-ones were obtained in moderate to good yields.