CT/MR Image Fusion in the Postoperative Assessment of Electrodes Implanted for Deep Brain Stimulation
CT/MR Image Fusion in the Postoperative Assessment of Electrodes Implanted for Deep Brain Stimulation
复制标题
DOI：
10.1159/000225973
复制
发表时间：
2009-01-01
影响因子：
1.7
通讯作者：
Ashkan, Keyoumars
中科院分区：
文献类型：
--
作者：
O'Gorman, Ruth L.;Jarosz, Josef M.;Ashkan, Keyoumars
背景/目标：立体定向术后成像对于验证脑深部电刺激（DBS）植入电极的位置至关重要。相对于CT，MRI提供了上级的DBS靶点可视化，但之前的不良事件加剧了对术后MRI风险的担忧。术前MRI与术后CT融合提供了一种评估电极位置的替代方法，但在此方法临床应用之前，必须建立图像配准精度。本研究的目的是定量评估三种不同的图像配准和融合方法的准确性。研究方法：对20例DBS手术患者（共35个电极）进行术前立体定向MRI和术后立体定向CT检查。使用三种不同的配准算法将术后CT与术前MRI配准并融合。在（未融合）术后CT和融合CT/MRI中，在立体定向坐标中确定每个电极头端的位置。CT和融合CT/MRI之间的尖端位置差异用于评价配准准确性。结果：沿横轴、前后轴和垂直轴的平均误差沿着分别为0.5、0.5和1 mm。结论：CT/MRI融合为DBS电极的术后识别提供了一种安全、实用的技术。版权所有（C）2009 S. Karger AG，巴塞尔
Background/Aims: Stereotactic postoperative imaging is essential for verification of the position of electrodes implanted for deep brain stimulation (DBS). MRI offers superior visualisation of the DBS targets relative to CT, but previous adverse incidents have heightened concerns about risks of postoperative MRI. Preoperative MRI fused with postoperative CT offers an alternative method for evaluating electrode position, but before this method can be clinically applied, the image registration accuracy must be established. The purpose of this study was to quantitatively assess the accuracy of three different image registration and fusion methods. Methods: Preoperative stereotactic MRI and postoperative stereotactic CT were acquired from 20 patients undergoing DBS surgery (35 electrodes in total). The postoperative CT was registered and fused with the preoperative MRI, using three different registration algorithms. The position of each electrode tip was determined in stereotactic coordinates both in the (unfused) postoperative CT and the fused CT/MRI. The difference in tip position between the CT and fused CT/MRI was used to evaluate the registration accuracy. Results: The mean error along the lateral, anteroposterior, and vertical axes was 0.5, 0.5, and 1 mm, respectively. Conclusions: CT/MRI fusion provides a safe, practical technique for postoperative identification of DBS electrodes. Copyright (C) 2009 S. Karger AG, Basel