Blocking autophagy enhances meloxicam lethality to hepatocellular carcinoma by promotion of endoplasmic reticulum stress
Blocking autophagy enhances meloxicam lethality to hepatocellular carcinoma by promotion of endoplasmic reticulum stress
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DOI：
10.1111/cpr.12221
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发表时间：
2015-10
影响因子：
8.5
通讯作者：
J. Zhong;Xiaofeng Dong;P. Xiu;Fuhai Wang;Ju Liu;Honglong Wei;Zong-zhen Xu;Feng Liu;Tao Li
中科院分区：
文献类型：
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作者：
J. Zhong;Xiaofeng Dong;P. Xiu;Fuhai Wang;Ju Liu;Honglong Wei;Zong-zhen Xu;Feng Liu;Tao Li
美洛昔康是一种选择性的环氧合酶-2(COX-2)抑制剂，已被证明对多种恶性肿瘤具有抗肿瘤作用。然而，到目前为止，美洛昔康抗肝细胞癌作用的机制尚不清楚。
Meloxicam, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has been demonstrated to exert anti‐tumour effects against various malignancies. However, up to now, mechanisms involved in meloxicam anti‐hepatocellular carcinoma effects have remained unclear.