Dividing the Child
Dividing the Child
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分割孩子
DOI：
10.1023/a:1022320801661
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发表时间：
2004
期刊：
影响因子：
1.5
通讯作者：
D. Haig
中科院分区：
文献类型：
--
作者：
F. Úbeda;D. Haig
基因组印记的进化被看作是一个经济优化问题，使用进化博弈论的工具进行分析。我们特别考虑了在现在和未来后代之间分配母体资源的遗传冲突。五组基因，具有相同的利益，但集之间的不同利益，被认为是代理人：母亲的等位基因（Mater），父亲的等位基因（Pater），无印记的后代等位基因（Filius），和母亲和父亲起源的印记后代等位基因（Matris和Patris）。健身功能，推导出每个代理和参数空间中，有冲突的定义。三个潜在的冲突被认为是：母亲和后代之间（Mater vs. Filius）;后代中母系和父系起源的等位基因之间（Matris vs. s父亲）和母亲和后代的父系来源的等位基因之间（Mater v.s. Patris）。
The evolution of genomic imprinting is viewed as a problem of economic optimization that is analyzed using the tools of evolutionary game theory. We specifically consider genetic conflicts over the allocation of maternal resources between present and future offspring. Five sets of genes, with the same interests within sets but distinct interests between sets, are considered as agents: maternal alleles (Mater), paternal alleles (Pater), unimprinted offspring alleles (Filius), and imprinted offspring alleles of maternal and paternal origin (Matris and Patris). Fitness functions are derived for each agent and the parameter space in which there is conflict defined. Three potential conflicts are considered: between mother and offspring (Mater v.s. Filius); between alleles of maternal and paternal origin within offspring (Matris v.s. Patris) and between mothers and the paternally derived alleles of offspring (Mater v.s. Patris).