Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle.
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle.
复制标题
Gaur基因组揭示了驯化牛精子气味受体的扩增。
DOI:
10.1186/s12864-022-08561-1
复制
发表时间:
2022-05-04
期刊:
影响因子:
4.4
通讯作者:
中科院分区:
文献类型:
--
作者:
The gaur (Bos gaurus) is the largest extant wild bovine species, native to South and Southeast Asia, with unique traits, and is listed as vulnerable by the International Union for Conservation of Nature (IUCN). We report the first gaur reference genome and identify three biological pathways including lysozyme activity, proton transmembrane transporter activity, and oxygen transport with significant changes in gene copy number in gaur compared to other mammals. These may reflect adaptation to challenges related to climate and nutrition. Comparative analyses with domesticated indicine (Bos indicus) and taurine (Bos taurus) cattle revealed genomic signatures of artificial selection, including the expansion of sperm odorant receptor genes in domesticated cattle, which may have important implications for understanding selection for male fertility. Apart from aiding dissection of economically important traits, the gaur genome will also provide the foundation to conserve the species. The online version contains supplementary material available at 10.1186/s12864-022-08561-1.
登录
查看更多内容
影响因子:
4.9
作者:
Bao W;Kojima KK;Kohany O
通讯作者:
Kohany O
影响因子:
14.9
作者:
Frankish A;Diekhans M;Ferreira AM;Johnson R;Jungreis I;Loveland J;Mudge JM;Sisu C;Wright J;Armstrong J;Barnes I;Berry A;Bignell A;Carbonell Sala S;Chrast J;Cunningham F;Di Domenico T;Donaldson S;Fiddes IT;García Girón C;Gonzalez JM;Grego T;Hardy M;Hourlier T;Hunt T;Izuogu OG;Lagarde J;Martin FJ;Martínez L;Mohanan S;Muir P;Navarro FCP;Parker A;Pei B;Pozo F;Ruffier M;Schmitt BM;Stapleton E;Suner MM;Sycheva I;Uszczynska-Ratajczak B;Xu J;Yates A;Zerbino D;Zhang Y;Aken B;Choudhary JS;Gerstein M;Guigó R;Hubbard TJP;Kellis M;Paten B;Reymond A;Tress ML;Flicek P
通讯作者:
Flicek P
影响因子:
3.5
作者:
Ali MA;Wang Y;Qin Z;Yuan X;Zhang Y;Zeng C
通讯作者:
Zeng C
影响因子:
3.1
作者:
GALLAGHER, DS;WOMACK, JE
通讯作者:
WOMACK, JE
影响因子:
2.8
作者:
FIELDS, MJ;HENTGES, JF;CORNELISSE, KW
通讯作者:
CORNELISSE, KW