Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
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DOI:
10.1093/annonc/mdw324
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发表时间:
2016-09-01
期刊:
影响因子:
50.5
通讯作者:
Arnold, D.
Arnold, D.
中科院分区:
医学1区
文献类型:
--
作者:
Valle, J. W.;Borbath, I.;Arnold, D.

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胆道癌(BTC)占所有人类癌症的< 1%,占所有原发性肝癌的约10%-15%,主要出现在70年代,男性占少数(男女比例为1.2-1.5:1.0)。它们被细分为肝内胆管癌(iCCA)和肝实质外肝外胆管癌(eCCA),前者起源于肝脏内的胆道树;后者又细分为肝门周围胆管癌(pCCA或Klatskin肿瘤)和远端胆管癌(dCCA)[2], iCCA发生率为10%-20%,pCCA发生率为50%,eCCA发生率为30%-40%。
Biliary tract cancer (BTC), comprising< 1% of all human cancers and∼ 10%–15% of all primary liver cancers, presents mostly in the seventh decade with a small male predominance (male: female ratio of 1.2–1.5: 1.0)[1]. They are subclassified as intrahepatic cholangiocarcinoma (iCCA), originating from the biliary tree within the liver, and extrahepatic cholangiocarcinoma (eCCA), outside the liver parenchyma; the latter is further subdivided into perihilar cholangiocarcinoma (pCCA or Klatskin tumour) and distal cholangiocarcinoma (dCCA)[2], with a frequency of 10%–20% iCCA, 50% pCCA and 30%–40% eCCA.