Uterine transplantation: towards clinical application
Uterine transplantation: towards clinical application
复制标题
子宫移植：走向临床应用
DOI：
10.1159/000350226
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Aoki D.
中科院分区：
文献类型：
--
作者：
Kisu I;Banno K;Suganuma N;Aoki D.
我怀着极大的兴趣阅读了Ozkan等人最近的报告。[1]他于2011年8月在土耳其进行了第二次人类子宫移植（UTx）。供体是一名22岁的因交通事故而脑死亡的患者，受体是一名21岁的Rokitansky综合征患者。术后第20天月经恢复，并持续周期性无明显排斥反应。目前，在手术后1年以上，正在尝试基于胚胎植入的妊娠。近年来，辅助生殖技术有了显着改善，许多不孕症患者使用该技术生下了孩子。然而，由于子宫缺失或无功能而导致不孕的妇女目前除了妊娠代孕外，没有选择有遗传联系的孩子的选择，这在许多国家受到法律的、道德和宗教问题的限制。
I read with great interest the recent report by Ozkan et al.[1], who performed the second uterine transplantation (UTx) in humans in August 2011 in Turkey. The donor was a patient aged 22 years who was braindead due to a traffic accident and the recipient was a patient aged 21 years with Rokitansky syndrome. Menstruation resumed on postoperative day 20 and continued cyclically without marked rejection. At present, at more than 1 year after surgery, pregnancy based on embryo implantation is being attempted.Assisted reproductive technology has improved markedly in recent years and many infertile patients have had children using this technology. However, women with infertility due to an absent or nonfunctional uterus currently have no option of having a genetically linked child, other than gestational surrogacy, which is restricted by legal, ethical and religious issues in many countries.